iPTMnet Report for Q96FW1 (OTUB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96FW1 / OTUB1_HUMAN
Protein Name Ubiquitin thioesterase OTUB1
Gene Name Name: OTUB1
Synonyms:OTB1,OTU1;ORFNames:HSPC263;
Organism Homo sapiens (Human)

PRO ID PR:Q96FW1
DAG View
PRO Name ubiquitin thioesterase OTUB1 (human)
Definition A ubiquitin thioesterase OTUB1 that is encoded in the genome of human.
Short Label hOTUB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96FW1 (OTUB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
K10 Sumoylation PhosphoSitePlus
S16 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 25872870
S18 Phosphorylation P36897 (TGFBR1) PhosphoSitePlus 25872870
Y26 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 35927303
S55 Phosphorylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
C91 S-Nitrosylation dbSNO 26338901
S108 Phosphorylation PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K122 Methylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
K188 Sumoylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S16 Phosphorylation HPRD 18669648
S18 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S161 F161 Biomuta DOID:4159 / skin cancer [ cosmic ]