iPTMnet Report for Q96FV9 (THOC1)
Protein Information
UniProt AC / UniProt ID | Q96FV9 / THOC1_HUMAN |
Protein Name | THO complex subunit 1 |
Gene Name | Name: THOC1 Synonyms:HPR1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96FV9 |
PRO Name | THO complex subunit 1 (human) |
Definition | A THO complex subunit 1 that is encoded in the genome of human. |
Short Label | hTHOC1 |
Category | organism-gene |
Q96FV9 (THOC1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 20068231 | ||
S2 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 20068231, ... | ||
T4 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
K31 | Sumoylation | score1 | PhosphoSitePlus | |||
K31 | Ubiquitination | score1 | PhosphoSitePlus | |||
K133 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K237 | Ubiquitination | score1 | PhosphoSitePlus | |||
K258 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y263 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K272 | Acetylation | score1 | PhosphoSitePlus | |||
Y274 | Phosphorylation | score1 | PhosphoSitePlus | |||
K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
K300 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
S313 | Phosphorylation | score1 | PhosphoSitePlus | |||
S315 | Phosphorylation | score1 | PhosphoSitePlus | |||
K376 | Ubiquitination | score1 | PhosphoSitePlus | |||
K392 | Ubiquitination | score1 | PhosphoSitePlus | |||
K401 | Ubiquitination | score1 | PhosphoSitePlus | |||
K408 | Sumoylation | score1 | PhosphoSitePlus | |||
K425 | Methylation | score1 | PhosphoSitePlus | |||
K425 | Ubiquitination | score1 | PhosphoSitePlus | |||
T428 | Phosphorylation | score1 | PhosphoSitePlus | |||
K430 | Ubiquitination | score1 | PhosphoSitePlus | |||
T439 | Phosphorylation | score1 | PhosphoSitePlus | |||
K453 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y521 | Phosphorylation | score1 | PhosphoSitePlus | |||
S537 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T542 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S560 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15302935, 23186163, 17081983, ... | ||
K580 | Ubiquitination | score1 | PhosphoSitePlus | |||
K595 | Sumoylation | score1 | PhosphoSitePlus | |||
K595 | Ubiquitination | score1 | PhosphoSitePlus | |||
S640 | Phosphorylation | score1 | PhosphoSitePlus | |||
S648 | Phosphorylation | score1 | PhosphoSitePlus | |||
S657 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T4 | K4 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K376 | E376 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc, tcga ] | |
K425 | E425 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K430 | N430 | Biomuta | DOID:363 / uterine cancer [ icgc ] |