iPTMnet Report for Q96FE5 (LINGO1)
Protein Information
UniProt AC / UniProt ID | Q96FE5 / LIGO1_HUMAN |
Protein Name | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 precursor |
Gene Name | Name: LINGO1 Synonyms:LERN1,LRRN6A;ORFNames:UNQ201/PRO227; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96FE5 |
PRO Name | leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (human) |
Definition | A leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 that is encoded in the genome of human. |
Short Label | hLINGO1 |
Category | organism-gene |
Q96FE5 (LINGO1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
N144 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
N202 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
N264 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
N274 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
N293 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y296 | Phosphorylation | score1 | PhosphoSitePlus | |||
S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
T301 | Phosphorylation | score1 | PhosphoSitePlus | |||
N341 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
N492 | N-Glycosylation | score3 | GlyGen UniProt | 17005555 | ||
S602 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S14 | N14 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S300 | G300 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S300 | R300 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |