iPTMnet Report for Q96FC9 (DDX11)
Protein Information
| UniProt AC / UniProt ID | Q96FC9 / DDX11_HUMAN |
| Protein Name | ATP-dependent DNA helicase DDX11 |
| Gene Name | Name: DDX11 Synonyms:CHL1,CHLR1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96FC9 |
| PRO Name | ATP-dependent DNA helicase DDX11 (human) |
| Definition | An ATP-dependent DNA helicase DDX11 that is encoded in the genome of human. |
| Short Label | hDDX11 |
| Category | organism-gene |
Q96FC9 (DDX11) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T104 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y202 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S204 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K253 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S262 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K303 | Sumoylation | score1 | PhosphoSitePlus | |||
| K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K460 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K507 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K526 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T541 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T542 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S589 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K596 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K611 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K722 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K733 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K734 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K740 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y752 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T818 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T825 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S204 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S274 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T541 | Phosphorylation | score0 | HPRD | 19651622 | ||
| T542 | Phosphorylation | score0 | HPRD | 19651622 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K811 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K830 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K839 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K853 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K873 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K897 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K154 | R154 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S204 | N204 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S237 | C237 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| K253 | M253 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K273 | R273 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| T541 | M541 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S753 | C753 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
DAG View