iPTMnet Report for Q96F07 (CYFIP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96F07 / CYFP2_HUMAN
Protein Name Cytoplasmic FMR1-interacting protein 2
Gene Name Name: CYFIP2
Synonyms:KIAA1168,PIR121;
Organism Homo sapiens (Human)

PRO ID PR:Q96F07
DAG View
PRO Name cytoplasmic FMR1-interacting protein 2 (human)
Definition A cytoplasmic FMR1-interacting protein 2 that is encoded in the genome of human.
Short Label hCYFIP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96F07 (CYFIP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K97 Ubiquitination PhosphoSitePlus
C98 S-Nitrosylation dbSNO 26338901
Y108 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
K110 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
K182 Acetylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K189 Acetylation PhosphoSitePlus
K197 Acetylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
T256 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
T419 Phosphorylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
C531 Methylation IEDB 31844290
K539 Ubiquitination PhosphoSitePlus
K545 Ubiquitination PhosphoSitePlus
S592 Phosphorylation PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
K756 Ubiquitination PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
K802 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K903 Ubiquitination PhosphoSitePlus
Y911 Phosphorylation PhosphoSitePlus
K916 Ubiquitination PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
K982 Ubiquitination PhosphoSitePlus
Y991 Phosphorylation PhosphoSitePlus
K1062 Acetylation PhosphoSitePlus   UniProt 19608861
K1062 Ubiquitination PhosphoSitePlus
K1072 Ubiquitination PhosphoSitePlus
K1077 Ubiquitination PhosphoSitePlus
Y1078 Phosphorylation PhosphoSitePlus
T1092 Phosphorylation PhosphoSitePlus
K1107 Ubiquitination PhosphoSitePlus
C1176 Methylation IEDB 31844290
K1216 Ubiquitination PhosphoSitePlus
K1221 Ubiquitination PhosphoSitePlus
K1234 Acetylation PhosphoSitePlus
K1234 Ubiquitination PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
K1251 Ubiquitination PhosphoSitePlus
C1265 S-Nitrosylation dbSNO 26338901
T1276 O-Glycosylation GlyGen 28657654
T1277 O-Glycosylation GlyGen 23301498, 34725712, 28657654
C1278 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
S582 Phosphorylation PhosphoSitePlus
T1067 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K197 M197 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y254 H254 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K260 N260 Biomuta DOID:4159 / skin cancer [ cosmic ]
K320 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K331 N331 Biomuta DOID:1319 / brain cancer [ cosmic ]
K421 N421 Biomuta DOID:4159 / skin cancer [ cosmic ]
S508 G508 Biomuta DOID:10534 / stomach cancer [ cosmic ]
C531 S531 Biomuta DOID:1324 / lung cancer [ cosmic ]
K802 I802 Biomuta DOID:263 / kidney cancer [ cosmic ]
K916 N916 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y991 N991 Biomuta DOID:1324 / lung cancer [ cosmic ]
K1077 M1077 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1077 T1077 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K1221 N1221 Biomuta DOID:1612 / breast cancer [ cosmic ]
K1248 N1248 Biomuta DOID:4159 / skin cancer [ cosmic ]