Protein Information

Cytoscape View

UniProt AC / UniProt ID Q96EQ8 / RN125_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF125
Gene Name Name: RNF125
Organism Homo sapiens (Human)

DAG View
PRO Name E3 ubiquitin-protein ligase RNF125 (human)
Definition An E3 ubiquitin-protein ligase RNF125 that is encoded in the genome of human.
Short Label hRNF125
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q96EQ8 (RNF125) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 17990982
K69 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
Y97 Phosphorylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K69 M69 Biomuta DOID:3070 / malignant glioma [ tcga ]
K98 N98 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:4362 / cervical cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ tcga ]
K125 N125 Biomuta DOID:3571 / liver cancer [ icgc ]