iPTMnet Report for Q96EQ8 (RNF125)
Protein Information
| UniProt AC / UniProt ID | Q96EQ8 / RN125_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase RNF125 |
| Gene Name | Name: RNF125 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96EQ8 |
| PRO Name | E3 ubiquitin-protein ligase RNF125 (human) |
| Definition | An E3 ubiquitin-protein ligase RNF125 that is encoded in the genome of human. |
| Short Label | hRNF125 |
| Category | organism-gene |
DAG ViewQ96EQ8 (RNF125) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score2 | UniProt | 17990982 | ||
| K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K91 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y97 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K125 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S95 | L95 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K98 | N98 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] |
