Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96EP0 / RNF31_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF31
Gene Name Name: RNF31
Synonyms:ZIBRA;
Organism Homo sapiens (Human)

PRO ID PR:Q96EP0
DAG View
PRO Name E3 ubiquitin-protein ligase RNF31 (human)
Definition An E3 ubiquitin-protein ligase RNF31 that is encoded in the genome of human.
Short Label hRNF31
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96EP0 (RNF31) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S19 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S436 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
S466 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569, ...18220336
S471 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
K579 Ubiquitination PhosphoSitePlus
T632 Phosphorylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
K640 Ubiquitination PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
K783 Ubiquitination PhosphoSitePlus
K784 Ubiquitination PhosphoSitePlus
S840 Phosphorylation PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
K873 Ubiquitination PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
S899 Phosphorylation PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
K944 Ubiquitination PhosphoSitePlus
K988 Ubiquitination PhosphoSitePlus
S1014 Phosphorylation PhosphoSitePlus
K1056 Ubiquitination PhosphoSitePlus
S1066 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S466 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S358 I358 Biomuta DOID:363 / uterine cancer [ icgc ]
S383 G383 Biomuta DOID:3571 / liver cancer [ cosmic ]
S436 C436 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S451 F451 Biomuta DOID:4159 / skin cancer [ cosmic ]
S471 G471 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S472 F472 Biomuta DOID:4159 / skin cancer [ cosmic ]
S493 G493 Biomuta DOID:3571 / liver cancer [ cosmic ]
S634 F634 Biomuta DOID:4159 / skin cancer [ cosmic ]
K640 N640 Biomuta DOID:1612 / breast cancer [ cosmic ]
S664 A664 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K735 N735 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
K783 N783 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K784 M784 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S877 L877 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S899 N899 Biomuta DOID:1319 / brain cancer [ cosmic ]
K910 I910 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]