iPTMnet Report for Q96EN8 (MOCOS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96EN8 / MOCOS_HUMAN
Protein Name Molybdenum cofactor sulfurase
Gene Name Name: MOCOS
Organism Homo sapiens (Human)

PRO ID PR:Q96EN8
DAG View
PRO Name molybdenum cofactor sulfurase (human)
Definition A molybdenum cofactor sulfurase that is encoded in the genome of human.
Short Label hMOCOS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96EN8 (MOCOS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S34 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
T162 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
S528 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243, ...20068231
S530 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20058876, 16964243, 18767875, ...15302935, 17322306, 18669648, 23186163, 20068231
K629 Acetylation PhosphoSitePlus
K651 Ubiquitination PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
K762 Ubiquitination PhosphoSitePlus
K830 Ubiquitination PhosphoSitePlus
K882 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K220 E220 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S528 C528 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K629 N629 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K706 E706 Biomuta DOID:9256 / colorectal cancer [ icgc ]