iPTMnet Report for Q96EL3 (MRPL53)
Protein Information
| UniProt AC / UniProt ID | Q96EL3 / RM53_HUMAN |
| Protein Name | Large ribosomal subunit protein mL53 precursor |
| Gene Name | Name: MRPL53 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96EL3 |
| PRO Name | 39S ribosomal protein L53, mitochondrial (human) |
| Definition | A 39S ribosomal protein L53, mitochondrial that is encoded in the genome of human. |
| Short Label | hMRPL53 |
| Category | organism-gene |
Q96EL3 (MRPL53) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| C21 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C49 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| C63 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S92 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
| T110 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C21 | S21 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| K41 | R41 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| C49 | F49 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S92 | F92 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] |
DAG View