Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96EL3 / RM53_HUMAN
Protein Name Large ribosomal subunit protein mL53 precursor
Gene Name Name: MRPL53
Organism Homo sapiens (Human)

PRO ID PR:Q96EL3
DAG View
PRO Name 39S ribosomal protein L53, mitochondrial (human)
Definition A 39S ribosomal protein L53, mitochondrial that is encoded in the genome of human.
Short Label hMRPL53
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96EL3 (MRPL53) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C21 S-Nitrosylation dbSNO 19483679
K41 Ubiquitination PhosphoSitePlus
C49 S-Nitrosylation dbSNO 26338901
C63 S-Nitrosylation dbSNO 26338901
S92 Phosphorylation HPRD   PhosphoSitePlus 20068231
T110 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C21 S21 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K41 R41 Biomuta DOID:4159 / skin cancer [ cosmic ]
C49 F49 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S92 F92 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]