iPTMnet Report for Q96EK4 (THAP11)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96EK4 / THA11_HUMAN
Protein Name THAP domain-containing protein 11
Gene Name Name: THAP11
ORFNames:HRIHFB2206;
Organism Homo sapiens (Human)

PRO ID PR:Q96EK4
DAG View
PRO Name THAP domain-containing protein 11 (human)
Definition A THAP domain-containing protein 11 that is encoded in the genome of human.
Short Label hTHAP11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96EK4 (THAP11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K19 Ubiquitination PhosphoSitePlus
T25 Phosphorylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
R42 Methylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
R83 Methylation PhosphoSitePlus
R88 Methylation PhosphoSitePlus
T163 O-Glycosylation GlyGen 34019948, 29351928
K274 Ubiquitination PhosphoSitePlus
S281 Phosphorylation HPRD   PhosphoSitePlus 20068231
K291 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T25 M25 Biomuta DOID:363 / uterine cancer [ icgc ]
K38 N38 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T78 S78 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R83 C83 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R88 P88 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K274 N274 Biomuta DOID:1319 / brain cancer [ icgc ]
K274 R274 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]