iPTMnet Report for Q96E39 (RBMXL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96E39 / RMXL1_HUMAN
Protein Name RNA binding motif protein, X-linked-like-1
Gene Name Name: RBMXL1
Organism Homo sapiens (Human)

PRO ID PR:Q96E39
DAG View
PRO Name RNA binding motif protein, X-linked-like-1 (human)
Definition An RNA binding motif protein, X-linked-like-1 that is encoded in the genome of human.
Short Label hRBMXL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96E39 (RBMXL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K9 Acetylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
T17 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
R49 Methylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
K63 Acetylation PhosphoSitePlus
K63 Sumoylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K72 Acetylation PhosphoSitePlus
S73 Phosphorylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K80 Sumoylation PhosphoSitePlus
K86 Methylation PhosphoSitePlus
S88 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 21406692, 20068231, ...18452278
R91 Methylation PhosphoSitePlus
R93 Methylation PhosphoSitePlus
R101 Methylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
R103 Methylation PhosphoSitePlus
R107 Methylation PhosphoSitePlus
R113 Methylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
R120 Methylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
R125 Methylation PhosphoSitePlus
Y134 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
R144 Methylation PhosphoSitePlus
K150 Acetylation PhosphoSitePlus
K150 Methylation PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
R151 Methylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
R164 Methylation PhosphoSitePlus
R172 Methylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
R180 Methylation PhosphoSitePlus
R185 Methylation PhosphoSitePlus
R187 Methylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
R195 Methylation PhosphoSitePlus
Y206 Phosphorylation HPRD   PhosphoSitePlus 17081983
S208 Phosphorylation HPRD   PhosphoSitePlus 17081983, 18491316, 16964243, ...18452278
Y214 Phosphorylation PhosphoSitePlus
S215 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
K217 Acetylation PhosphoSitePlus
K217 Methylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
Y234 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
Y272 Phosphorylation HPRD   PhosphoSitePlus 17081983
S273 Phosphorylation HPRD   PhosphoSitePlus 17081983
S277 Phosphorylation HPRD   PhosphoSitePlus 17081983
S280 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
Y285 Phosphorylation PhosphoSitePlus
S287 Phosphorylation HPRD   PhosphoSitePlus 17081983
Y288 Phosphorylation HPRD   PhosphoSitePlus 17081983
S291 Phosphorylation HPRD   PhosphoSitePlus 17081983
R292 Methylation PhosphoSitePlus
R298 Methylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
Y304 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
R317 Methylation PhosphoSitePlus
Y320 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus
Y327 Phosphorylation PhosphoSitePlus
S328 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
Y335 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
R343 Methylation PhosphoSitePlus
R346 Methylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
R354 Methylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
Y363 Phosphorylation PhosphoSitePlus
R368 Methylation PhosphoSitePlus
R372 Methylation PhosphoSitePlus
R380 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K9 N9 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1785 / pituitary cancer [ cosmic ]
R49 S49 Biomuta DOID:1324 / lung cancer [ cosmic ]
S73 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
S73 L73 Biomuta DOID:4159 / skin cancer [ cosmic ]
K80 N80 Biomuta DOID:1319 / brain cancer [ icgc ]
R91 S91 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
R101 K101 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R113 K113 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R125 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S135 F135 Biomuta DOID:4159 / skin cancer [ cosmic ]
S142 Y142 Biomuta DOID:363 / uterine cancer [ icgc ]
R144 W144 Biomuta DOID:1324 / lung cancer [ cosmic ]
S161 P161 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
R172 H172 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
R172 C172 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R185 C185 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
R185 H185 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S189 N189 Biomuta DOID:4362 / cervical cancer [ icgc ]
R195 Q195 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R195 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S208 P208 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S208 F208 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y214 F214 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y214 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
S215 C215 Biomuta DOID:263 / kidney cancer [ cosmic ]
S215 P215 Biomuta DOID:1319 / brain cancer [ icgc ]
S219 T219 Biomuta [ cosmic ]
S222 I222 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y225 H225 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y234 C234 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y243 S243 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y255 C255 Biomuta DOID:1612 / breast cancer [ cosmic ]
S257 L257 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y281 H281 Biomuta DOID:184 / bone cancer [ cosmic ]
S291 L291 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R292 H292 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
R292 C292 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R298 Q298 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y310 C310 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S314 G314 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R317 H317 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R317 C317 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R317 P317 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R317 S317 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S326 G326 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y327 F327 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
R343 T343 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R368 H368 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ]
R372 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
R380 Q380 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]