iPTMnet Report for Q96DY7 (MTBP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96DY7 / MTBP_HUMAN
Protein Name Mdm2-binding protein
Gene Name Name: MTBP
Organism Homo sapiens (Human)

PRO ID PR:Q96DY7
DAG View
PRO Name Mdm2-binding protein (human)
Definition An Mdm2-binding protein that is encoded in the genome of human.
Short Label hMTBP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96DY7 (MTBP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K51 Ubiquitination PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
C358 Methylation IEDB 31844290
Y379 Phosphorylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
S539 Phosphorylation PhosphoSitePlus   RLIMS-P 33608586
K570 Ubiquitination PhosphoSitePlus
T577 Phosphorylation PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus   UniProt 23186163
K604 Ubiquitination PhosphoSitePlus
K608 Ubiquitination PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
T635 Phosphorylation PhosphoSitePlus   RLIMS-P 33608586
S639 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 18669648, 33608586, 23186163, ...20068231
K642 Ubiquitination PhosphoSitePlus
T687 Phosphorylation PhosphoSitePlus
S703 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33608586, 19690332
S707 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 33608586, 19690332
S738 Phosphorylation PhosphoSitePlus
K739 Methylation PhosphoSitePlus
K752 Sumoylation PhosphoSitePlus
S753 Phosphorylation PhosphoSitePlus
S755 Phosphorylation PhosphoSitePlus
S756 Phosphorylation PhosphoSitePlus
S758 Phosphorylation PhosphoSitePlus
S796 Phosphorylation PhosphoSitePlus
T804 Phosphorylation PhosphoSitePlus
T831 O-Glycosylation GlyGen 30379171
K844 Ubiquitination PhosphoSitePlus
S846 Phosphorylation PhosphoSitePlus
T855 Phosphorylation PhosphoSitePlus
K866 Ubiquitination PhosphoSitePlus
K883 Ubiquitination PhosphoSitePlus
K884 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S639 Phosphorylation HPRD 19413330, 18669648, 19664994, ...19664995, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K267 R267 Biomuta DOID:363 / uterine cancer [ icgc ]
K281 N281 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K627 R627 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K630 N630 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S738 F738 Biomuta [ cosmic ]
S756 L756 Biomuta DOID:4159 / skin cancer [ cosmic ]
S758 F758 Biomuta DOID:4159 / skin cancer [ cosmic ]
S796 T796 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S846 G846 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]