Protein Information

Cytoscape View

UniProt AC / UniProt ID Q96DX4 / RSPRY_HUMAN
Protein Name RING finger and SPRY domain-containing protein 1 precursor
Gene Name Name: RSPRY1
Organism Homo sapiens (Human)

DAG View
PRO Name RING finger and SPRY domain-containing protein 1 (human)
Definition A RING finger and SPRY domain-containing protein 1 that is encoded in the genome of human.
Short Label hRSPRY1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q96DX4 (RSPRY1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
S144 O-Glycosylation GlyGen 29351928
K177 Ubiquitination PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S55 N55 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S144 C144 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y330 C330 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
K415 R415 Biomuta DOID:1324 / lung cancer [ tcga ]
S545 G545 Biomuta DOID:1909 / melanoma [ cosmic ]