iPTMnet Report for Q96DT6 (ATG4C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96DT6 / ATG4C_HUMAN
Protein Name Cysteine protease ATG4C
Gene Name Name: ATG4C
Synonyms:APG4C;
Organism Homo sapiens (Human)

PRO ID PR:Q96DT6
DAG View
PRO Name cysteine protease ATG4C (human)
Definition A cysteine protease ATG4C that is encoded in the genome of human.
Short Label hATG4C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96DT6 (ATG4C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K15 Ubiquitination PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
Y25 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
Y185 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
C349 Methylation IEDB 31844290
S369 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
C382 Methylation IEDB 31844290
T383 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus   UniProt 23186163
T452 Phosphorylation PhosphoSitePlus   UniProt 23186163


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S18 C18 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S166 L166 Biomuta DOID:1324 / lung cancer [ cosmic ]
K403 N403 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]