Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96DR7 / ARHGQ_HUMAN
Protein Name Rho guanine nucleotide exchange factor 26
Gene Name Name: ARHGEF26
Synonyms:SGEF;ORFNames:HMFN1864;
Organism Homo sapiens (Human)

PRO ID PR:Q96DR7
DAG View
PRO Name Rho guanine nucleotide exchange factor 26 (human)
Definition A Rho guanine nucleotide exchange factor 26 that is encoded in the genome of human.
Short Label hARHGEF26
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96DR7 (ARHGEF26) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation PhosphoSitePlus   UniProt 21406692
T76 Phosphorylation PhosphoSitePlus
R79 Methylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S98 Phosphorylation PhosphoSitePlus
Y101 Phosphorylation PhosphoSitePlus
S124 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
Y317 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S340 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus   UniProt 21406692, 19690332, 24275569
S396 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
K531 Ubiquitination PhosphoSitePlus
Y532 Phosphorylation PhosphoSitePlus
Y538 Phosphorylation PhosphoSitePlus
K611 Acetylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus
Y735 Phosphorylation PhosphoSitePlus
T775 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S80 Phosphorylation HPRD 19664994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S239 N239 Biomuta DOID:10534 / stomach cancer [ tcga ]
Y380 H380 Biomuta DOID:363 / uterine cancer [ tcga ]
K611 Q611 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]