iPTMnet Report for Q96DN2 (VWCE)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96DN2 / VWCE_HUMAN
Protein Name von Willebrand factor C and EGF domain-containing protein precursor
Gene Name Name: VWCE
Synonyms:URG11;
Organism Homo sapiens (Human)

PRO ID PR:Q96DN2
DAG View
PRO Name von Willebrand factor C and EGF domain-containing protein (human)
Definition A von Willebrand factor C and EGF domain-containing protein that is encoded in the genome of human.
Short Label hVWCE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96DN2 (VWCE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S197 Phosphorylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S320 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
S816 O-Glycosylation GlyGen 30459171
T833 O-Glycosylation GlyGen 30459171
S861 O-Glycosylation GlyGen 30459171
S879 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S885 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T911 O-Glycosylation GlyGen 30459171
T935 O-Glycosylation GlyGen 30459171


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S197 N197 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y201 C201 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S370 L370 Biomuta DOID:4159 / skin cancer [ cosmic ]
S816 I816 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S885 F885 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]