iPTMnet Report for Q96DH6 (MSI2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96DH6 / MSI2H_HUMAN
Protein Name RNA-binding protein Musashi homolog 2
Gene Name Name: MSI2
Organism Homo sapiens (Human)

PRO ID PR:Q96DH6
DAG View
PRO Name RNA-binding protein Musashi homolog 2 (human)
Definition An RNA-binding protein Musashi homolog 2 that is encoded in the genome of human.
Short Label hMSI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96DH6 (MSI2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
E2 Acetylation UniProt 20068231
S6 Phosphorylation PhosphoSitePlus   UniProt 23186163
T9 Phosphorylation PhosphoSitePlus
N14 Phosphorylation UniProt 20068231
S16 Phosphorylation PhosphoSitePlus
T32 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
K43 Acetylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K178 Ubiquitination PhosphoSitePlus
R197 Methylation PhosphoSitePlus
R199 Methylation PhosphoSitePlus
R201 Methylation PhosphoSitePlus
R228 Methylation PhosphoSitePlus   UniProt 24129315
R261 Methylation PhosphoSitePlus   UniProt 24129315
Site PTM Type PTM Enzyme Score Source PMID
T146 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 20068231
S14 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231
T142 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T32 P32 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S74 G74 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
K94 E94 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K104 N104 Biomuta DOID:3571 / liver cancer [ cosmic ]
K145 E145 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R199 Q199 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R199 W199 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R201 W201 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R228 C228 Biomuta DOID:9256 / colorectal cancer [ cosmic ]