iPTMnet Report for Q96DG6 (CMBL)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96DG6 / CMBL_HUMAN
Protein Name Carboxymethylenebutenolidase homolog
Gene Name Name: CMBL
Organism Homo sapiens (Human)

PRO ID PR:Q96DG6
DAG View
PRO Name carboxymethylenebutenolidase homolog (human)
Definition A carboxymethylenebutenolidase that is encoded in the genome of human.
Short Label hCMBL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96DG6 (CMBL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y6 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
Y33 Phosphorylation PhosphoSitePlus
K36 Acetylation PhosphoSitePlus   UniProt 19608861
K36 Ubiquitination PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
Y116 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
Y165 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
K193 Acetylation PhosphoSitePlus
K193 Ubiquitination PhosphoSitePlus
K199 Methylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus   UniProt 24275569
K227 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y33 H33 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K193 N193 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K218 E218 Biomuta DOID:1324 / lung cancer [ cosmic ]
K218 N218 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]