iPTMnet Report for Q96D96 (HVCN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96D96 / HVCN1_HUMAN
Protein Name Voltage-gated hydrogen channel 1
Gene Name Name: HVCN1
Synonyms:VSOP;ORFNames:UNQ578/PRO1140;
Organism Homo sapiens (Human)

PRO ID PR:Q96D96
DAG View
PRO Name voltage-gated hydrogen channel 1 (human)
Definition A voltage-gated hydrogen channel 1 that is encoded in the genome of human.
Short Label hHVCN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96D96 (HVCN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K7 Ubiquitination PhosphoSitePlus
T29 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   UniProt 20037153
Y35 Phosphorylation PhosphoSitePlus
Y42 Phosphorylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
S97 Phosphorylation Q05655 (PRKCD) PhosphoSitePlus   UniProt 20037153
K232 Ubiquitination PhosphoSitePlus
K252 Acetylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y35 Phosphorylation HPRD 19901323
Site PTM Type PTM Enzyme Score Source PMID
T9 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y42 C42 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S77 R77 Biomuta DOID:3571 / liver cancer [ cosmic ]
S97 R97 Biomuta DOID:3571 / liver cancer [ cosmic ]