iPTMnet Report for Q96CW5 (TUBGCP3)
Protein Information
| UniProt AC / UniProt ID | Q96CW5 / GCP3_HUMAN |
| Protein Name | Gamma-tubulin complex component 3 |
| Gene Name | Name: TUBGCP3 Synonyms:GCP3; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96CW5 |
| PRO Name | gamma-tubulin complex component 3 (human) |
| Definition | A gamma-tubulin complex component 3 that is encoded in the genome of human. |
| Short Label | hTUBGCP3 |
| Category | organism-gene |
Q96CW5 (TUBGCP3) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| S8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score1 | IEDB | 32387766 | ||
| S113 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y131 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R135 | Methylation | score1 | PhosphoSitePlus | |||
| T138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y256 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K264 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K276 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K280 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T290 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K303 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K375 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K379 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K392 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K405 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y443 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K455 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K463 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K482 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S489 | Phosphorylation | score1 | IEDB | 30784271 | ||
| K505 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K511 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S515 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K543 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y544 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S614 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K689 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K831 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K837 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T866 | O-Glycosylation | score1 | GlyGen | 28510447, 29351928 | ||
| T867 | O-Glycosylation | score1 | GlyGen | 28510447, 29351928 | ||
| S872 | O-Glycosylation | score1 | GlyGen | 28510447, 29351928 | ||
| S896 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T899 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S904 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S905 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S480 | Phosphorylation | score0 | HPRD | 18767875 | ||
| S512 | Phosphorylation | score0 | HPRD | 18452278 | ||
| S839 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S896 | Phosphorylation | score0 | HPRD | 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K379 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S92 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S489 | L489 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| S512 | F512 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| Y544 | C544 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S614 | R614 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K831 | T831 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S905 | C905 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] |
DAG View