iPTMnet Report for Q96CW1 (AP2M1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96CW1 / AP2M1_HUMAN
Protein Name AP-2 complex subunit mu
Gene Name Name: AP2M1
Synonyms:CLAPM1,KIAA0109;
Organism Homo sapiens (Human)

PRO ID PR:Q96CW1
DAG View
PRO Name AP-2 complex subunit mu (human)
Definition An AP-2 complex subunit mu that is encoded in the genome of human.
Short Label hAP2M1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96CW1 (AP2M1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation PhosphoSitePlus   UniProt 18691976
K139 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
T152 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
T156 Phosphorylation neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18691976, 23186163, 18158287, ...30605688, 11877457, 22916011, 24275569, 11877461
T156 Phosphorylation Q2M2I8 (AAK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11877457, 11877461
K203 Acetylation PhosphoSitePlus
C212 Methylation IEDB 31844290
C212 S-Nitrosylation dbSNO 2212679, 22126794
K219 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K227 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
K256 Acetylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K281 Ubiquitination PhosphoSitePlus
K304 Acetylation PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
K308 Acetylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
Y344 Phosphorylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S397 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
K420 Acetylation PhosphoSitePlus
K420 Ubiquitination PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus
T433 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18691976
S153 Phosphorylation HPRD 18691976
T156 Phosphorylation HPRD 18691976, 18767875, 19664994, ...8257432, 20058876
S236 Phosphorylation HPRD 18691976
Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation HPRD 18691976
T134 Phosphorylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
S151 Phosphorylation HPRD 18691976
T154 Phosphorylation HPRD   PhosphoSitePlus 18691976, 19664994, 20058876, ...18767875
S234 Phosphorylation HPRD 18691976


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046349 (hAP2M1/Phos:1) pT156 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T134 M134 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
K139 R139 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T154 I154 Biomuta DOID:4159 / skin cancer [ cosmic ]
T156 I156 Biomuta DOID:4159 / skin cancer [ cosmic ]
K304 E304 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K378 N378 Biomuta DOID:1324 / lung cancer [ cosmic ]
S397 C397 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K405 E405 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S414 N414 Biomuta DOID:3571 / liver cancer [ cosmic ]