iPTMnet Report for Q96CS7 (PLEKHB2)
Protein Information
| UniProt AC / UniProt ID | Q96CS7 / PKHB2_HUMAN |
| Protein Name | Pleckstrin homology domain-containing family B member 2 |
| Gene Name | Name: PLEKHB2 Synonyms:EVT2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96CS7 |
| PRO Name | pleckstrin homology domain-containing family B member 2 (human) |
| Definition | A pleckstrin homology domain-containing family B member 2 that is encoded in the genome of human. |
| Short Label | hPLEKHB2 |
| Category | organism-gene |
DAG ViewQ96CS7 (PLEKHB2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K17 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K46 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T58 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K71 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y144 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K17 | N17 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K46 | N46 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T58 | M58 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| T58 | A58 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
