iPTMnet Report for Q96CS3 (FAF2)
Protein Information
| UniProt AC / UniProt ID | Q96CS3 / FAF2_HUMAN |
| Protein Name | FAS-associated factor 2 |
| Gene Name | Name: FAF2 Synonyms:ETEA; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96CS3 |
| PRO Name | FAS-associated factor 2 (human) |
| Definition | A FAS-associated factor 2 that is encoded in the genome of human. |
| Short Label | hFAF2 |
| Category | organism-gene |
Q96CS3 (FAF2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| T10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T14 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K16 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y79 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 | ||
| S80 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S142 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K146 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K167 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K167 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K215 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T244 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K307 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K343 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K346 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S355 | O-Glycosylation | score1 | GlyGen | 35132862, 28510447 | ||
| S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K400 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T14 | K14 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K16 | E16 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S66 | L66 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T244 | I244 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View