Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96CN9 / GCC1_HUMAN
Protein Name GRIP and coiled-coil domain-containing protein 1
Gene Name Name: GCC1
Organism Homo sapiens (Human)

PRO ID PR:Q96CN9
DAG View
PRO Name GRIP and coiled-coil domain-containing protein 1 (human)
Definition A GRIP and coiled-coil domain-containing protein 1 that is encoded in the genome of human.
Short Label hGCC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96CN9 (GCC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S91 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K449 Acetylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus
T597 Phosphorylation HPRD   PhosphoSitePlus 20068231
K599 Ubiquitination PhosphoSitePlus
S620 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y722 Phosphorylation PhosphoSitePlus
T732 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S91 N91 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K252 T252 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S356 F356 Biomuta DOID:4159 / skin cancer [ cosmic ]
S414 R414 Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
S414 C414 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S416 F416 Biomuta DOID:4159 / skin cancer [ cosmic ]
T578 A578 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T578 I578 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T597 I597 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K599 N599 Biomuta DOID:363 / uterine cancer [ icgc ]
S620 R620 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T732 I732 Biomuta DOID:363 / uterine cancer [ icgc ]