iPTMnet Report for Q96CM8 (ACSF2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96CM8 / ACSF2_HUMAN
Protein Name Medium-chain acyl-CoA ligase ACSF2, mitochondrial precursor
Gene Name Name: ACSF2
ORFNames:UNQ493/PRO1009;
Organism Homo sapiens (Human)

PRO ID PR:Q96CM8
DAG View
PRO Name medium-chain acyl-CoA ligase ACSF2, mitochondrial (human)
Definition A medium-chain acyl-CoA ligase ACSF2, mitochondrial that is encoded in the genome of human.
Short Label hACSF2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96CM8 (ACSF2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
T53 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
K66 Acetylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
C254 Methylation IEDB 31844290
K296 Acetylation PhosphoSitePlus
T297 Phosphorylation IEDB 35494241
T417 O-Glycosylation GlyGen 29351928
Y466 Phosphorylation PhosphoSitePlus
Y472 Phosphorylation PhosphoSitePlus
T531 Phosphorylation PhosphoSitePlus
T564 Phosphorylation PhosphoSitePlus
Y592 Phosphorylation PhosphoSitePlus
T595 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y592 Phosphorylation HPRD 18491316
S597 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T53 M53 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S71 N71 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y466 H466 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, icgc ]
T595 I595 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]