iPTMnet Report for Q96CG3 (TIFA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96CG3 / TIFA_HUMAN
Protein Name TRAF-interacting protein with FHA domain-containing protein A
Gene Name Name: TIFA
Synonyms:T2BP;
Organism Homo sapiens (Human)

PRO ID PR:Q96CG3
DAG View
PRO Name TRAF-interacting protein with FHA domain-containing protein A (human)
Definition A TRAF-interacting protein with FHA domain-containing protein A that is encoded in the genome of human.
Short Label hTIFA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96CG3 (TIFA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
T9 Phosphorylation P31749 (AKT1) , O14965 (AURKA) PhosphoSitePlus   RLIMS-P   Signor   UniProt 26389808, 32420802, 22566686, ...27965388, 26068852, 30111836, 28069801
T12 Phosphorylation PhosphoSitePlus
T19 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
T177 Phosphorylation PhosphoSitePlus   RLIMS-P 36098982


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T19 M19 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K108 T108 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y113 C113 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]