iPTMnet Report for Q96C57 (CUSTOS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96C57 / CSTOS_HUMAN
Protein Name Protein CUSTOS
Gene Name Name: CUSTOS
Synonyms:C12orf43;
Organism Homo sapiens (Human)

PRO ID PR:Q96C57
DAG View
PRO Name protein CUSTOS (human)
Definition A protein CUSTOS that is encoded in the genome of human.
Short Label hCUSTOS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96C57 (CUSTOS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Acetylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus   UniProt 23186163
T78 Phosphorylation PhosphoSitePlus
T79 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S138 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S167 Phosphorylation PhosphoSitePlus
S175 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231
S179 Phosphorylation HPRD   PhosphoSitePlus 20068231, 18452278
T182 Phosphorylation PhosphoSitePlus   UniProt 23186163
S202 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
T210 Phosphorylation PhosphoSitePlus
T211 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163, ...20068231
T213 Phosphorylation HPRD   PhosphoSitePlus 19413330
S214 O-Glycosylation GlyGen 31373491
S223 Phosphorylation HPRD   PhosphoSitePlus 20068231
S232 Phosphorylation PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
S248 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S58 F58 Biomuta DOID:4159 / skin cancer [ cosmic ]
S138 F138 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S179 N179 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S179 C179 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S205 L205 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S223 P223 Biomuta DOID:1319 / brain cancer [ cosmic ]
S245 N245 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T247 I247 Biomuta DOID:4159 / skin cancer [ cosmic ]