iPTMnet Report for Q96BZ4 (PLD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BZ4 / PLD4_HUMAN
Protein Name 5'-3' exonuclease PLD4
Gene Name Name: PLD4
Synonyms:C14orf175;ORFNames:UNQ2488/PRO5775;
Organism Homo sapiens (Human)

PRO ID PR:Q96BZ4
DAG View
PRO Name 5'-3' exonuclease PLD4 (human)
Definition A 5'-3' exonuclease PLD4 that is encoded in the genome of human.
Short Label hPLD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BZ4 (PLD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N171 N-Glycosylation GlyGen 29391424
S173 O-Glycosylation GlyGen 28657654
N249 N-Glycosylation GlyGen 29391424, 24190977
K271 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
N281 N-Glycosylation GlyGen 29391424, 24190977
N403 N-Glycosylation GlyGen 29391424, 24190977
N417 N-Glycosylation GlyGen 29741879, 29391424, 24190977
N420 N-Glycosylation GlyGen 24190977
N427 N-Glycosylation GlyGen 24190977
T453 Phosphorylation phospho.ELM 16094384
T472 Phosphorylation HPRD   PhosphoSitePlus 16094384


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S173 F173 Biomuta [ cosmic ]
N427 S427 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T453 M453 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ]
T472 M472 Biomuta DOID:10534 / stomach cancer [ cosmic ]