iPTMnet Report for Q96BY6 (DOCK10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BY6 / DOC10_HUMAN
Protein Name Dedicator of cytokinesis protein 10
Gene Name Name: DOCK10
Synonyms:KIAA0694,ZIZ3;
Organism Homo sapiens (Human)

PRO ID PR:Q96BY6
DAG View
PRO Name dedicator of cytokinesis protein 10 (human)
Definition A dedicator of cytokinesis protein 10 that is encoded in the genome of human.
Short Label hDOCK10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BY6 (DOCK10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S167 Phosphorylation PhosphoSitePlus
T196 Phosphorylation PhosphoSitePlus
T200 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
T202 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
S220 Phosphorylation PhosphoSitePlus
Y221 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
Y526 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K538 Ubiquitination PhosphoSitePlus
C547 Methylation IEDB 31844290
K596 Ubiquitination PhosphoSitePlus
Y601 Phosphorylation PhosphoSitePlus
K680 Ubiquitination PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
Y765 Phosphorylation PhosphoSitePlus
K827 Ubiquitination PhosphoSitePlus
K834 Acetylation PhosphoSitePlus   UniProt 19608861
K834 Ubiquitination PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
K954 Ubiquitination PhosphoSitePlus
K969 Ubiquitination PhosphoSitePlus
K976 Ubiquitination PhosphoSitePlus
S1000 O-Glycosylation GlyGen 30379171, 29351928
S1085 Phosphorylation PhosphoSitePlus
T1228 Phosphorylation PhosphoSitePlus
S1232 Phosphorylation PhosphoSitePlus   UniProt 19690332
S1236 Phosphorylation PhosphoSitePlus
S1241 Phosphorylation PhosphoSitePlus
S1257 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
S1286 Phosphorylation PhosphoSitePlus
S1289 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087, 17081983
S1292 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 17081983, 19690332
S1295 Phosphorylation PhosphoSitePlus   UniProt 18088087, 17081983, 19690332
S1318 O-Glycosylation GlyGen 30379171, 29351928
S1318 Phosphorylation PhosphoSitePlus   UniProt 17081983, 19690332
S1322 Phosphorylation PhosphoSitePlus
T1323 Phosphorylation PhosphoSitePlus
Y1350 Phosphorylation PhosphoSitePlus
S1400 Phosphorylation PhosphoSitePlus
T1401 Phosphorylation PhosphoSitePlus
T1406 Phosphorylation PhosphoSitePlus
S1410 Phosphorylation PhosphoSitePlus
S1413 Phosphorylation PhosphoSitePlus
S1438 Phosphorylation PhosphoSitePlus
T1440 Phosphorylation IEDB   PhosphoSitePlus   UniProt 35494241, 19690332
K1447 Ubiquitination PhosphoSitePlus
S1451 Phosphorylation PhosphoSitePlus
K1593 Acetylation PhosphoSitePlus
S1602 Phosphorylation PhosphoSitePlus
K1655 Ubiquitination PhosphoSitePlus
Y1853 Phosphorylation PhosphoSitePlus
Y1854 Phosphorylation PhosphoSitePlus
S1869 Phosphorylation PhosphoSitePlus
K1902 Ubiquitination PhosphoSitePlus
Y1917 Phosphorylation PhosphoSitePlus
K1920 Ubiquitination PhosphoSitePlus
K1934 Ubiquitination PhosphoSitePlus
K1965 Ubiquitination PhosphoSitePlus
S2020 Phosphorylation PhosphoSitePlus
S2037 Phosphorylation PhosphoSitePlus
Y2076 Phosphorylation PhosphoSitePlus
T2084 Phosphorylation PhosphoSitePlus
K2095 Ubiquitination PhosphoSitePlus
K2120 Ubiquitination PhosphoSitePlus
Y2126 Phosphorylation PhosphoSitePlus
K2135 Ubiquitination PhosphoSitePlus
T2150 Phosphorylation PhosphoSitePlus
S2169 O-Glycosylation GlyGen 30379171, 29351928
S2183 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T196 Phosphorylation HPRD 18578522
T200 Phosphorylation HPRD 18088087
S1292 Phosphorylation HPRD 19651622, 18088087, 17081983
S1295 Phosphorylation HPRD 19651622, 18578522, 18088087, ...17081983
S1318 Phosphorylation HPRD 17081983
S1400 Phosphorylation HPRD 18077418
T1401 Phosphorylation HPRD 18077418
T1406 Phosphorylation HPRD 18077418
Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 Y35 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y130 H130 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S131 F131 Biomuta DOID:4159 / skin cancer [ cosmic ]
S151 F151 Biomuta DOID:4159 / skin cancer [ cosmic ]
T196 P196 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S205 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K528 N528 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K538 N538 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y765 D765 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K969 T969 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1000 L1000 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1085 F1085 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
S1236 Y1236 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1257 Y1257 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1289 C1289 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S1318 Y1318 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1400 Y1400 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1438 P1438 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1440 P1440 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T1440 N1440 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1593 T1593 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1602 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1602 P1602 Biomuta DOID:184 / bone cancer [ cosmic ]
Y1854 C1854 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1869 L1869 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1902 R1902 Biomuta DOID:4159 / skin cancer [ cosmic ]
S2037 Y2037 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T2084 P2084 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T2084 A2084 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K2095 Q2095 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]