iPTMnet Report for Q96BT3 (CENPT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BT3 / CENPT_HUMAN
Protein Name Centromere protein T
Gene Name Name: CENPT
Synonyms:C16orf56,ICEN22;
Organism Homo sapiens (Human)

PRO ID PR:Q96BT3
DAG View
PRO Name centromere protein T (human)
Definition A centromere protein T that is encoded in the genome of human.
Short Label hCENPT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BT3 (CENPT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus   RLIMS-P 28012276, 29629870
T27 Phosphorylation PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus   UniProt 21529714, 23186163, 20068231
T57 Phosphorylation PhosphoSitePlus
T85 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 28012276, 29629870, 20068231
S125 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S188 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
T192 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
T195 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 28012276, 25660545, 16565220
S201 Phosphorylation PhosphoSitePlus   RLIMS-P 28012276, 29629870
S257 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus   UniProt 23186163
S373 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S385 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S386 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
S397 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935, 18669648, ...19690332, 20068231
S400 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
T404 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
K457 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation HPRD 19007248
T11 Phosphorylation HPRD 19007248, 19691289
T45 Phosphorylation HPRD 19007248, 19664995
S47 Phosphorylation HPRD 19664995, 19691289, 20068231, ...19007248
T57 Phosphorylation HPRD 20068231
T85 Phosphorylation HPRD 19007248, 20068231
S184 Phosphorylation HPRD 20068231
S188 Phosphorylation HPRD 20068231, 16565220
T192 Phosphorylation HPRD 16565220
T195 Phosphorylation HPRD 16565220
S201 Phosphorylation HPRD 19007248
S373 Phosphorylation HPRD 17525332
S385 Phosphorylation HPRD 17525332, 18452278
S386 Phosphorylation HPRD 17525332, 18452278
S397 Phosphorylation HPRD 19413330, 19651622, 18669648, ...19691289, 20068231
T404 Phosphorylation HPRD 19691289
S407 Phosphorylation HPRD 19691289
S461 Phosphorylation HPRD 20068231
Y463 Phosphorylation HPRD 20068231
S468 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T27 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q96BT3 (CENPT) S201 Q9H081 (MIS12) unknown eFIP 28012276


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T45 A45 Biomuta DOID:4159 / skin cancer [ cosmic ]
T57 K57 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T57 M57 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
T57 R57 Biomuta [ cosmic ]
S257 F257 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S373 F373 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K457 N457 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]