iPTMnet Report for Q96BR5 (COA7)
Protein Information
| UniProt AC / UniProt ID | Q96BR5 / COA7_HUMAN |
| Protein Name | Cytochrome c oxidase assembly factor 7 |
| Gene Name | Name: COA7 Synonyms:C1orf163,RESA1,SELRC1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96BR5 |
| PRO Name | cytochrome c oxidase assembly factor 7 (human) |
| Definition | A cytochrome c oxidase assembly factor 7 that is encoded in the genome of human. |
| Short Label | hCOA7 |
| Category | organism-gene |
Q96BR5 (COA7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S68 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C71 | Methylation | score1 | IEDB | 31844290 | ||
| K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T86 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K133 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C179 | Methylation | score1 | IEDB | 31844290 | ||
| S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K59 | E59 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S68 | N68 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S70 | R70 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S70 | I70 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K133 | R133 | Biomuta | [ cosmic ] | |
| K206 | E206 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] |
DAG View