Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BP3 / PPWD1_HUMAN
Protein Name Peptidylprolyl isomerase domain and WD repeat-containing protein 1
Gene Name Name: PPWD1
Synonyms:KIAA0073;
Organism Homo sapiens (Human)

PRO ID PR:Q96BP3
DAG View
PRO Name peptidylprolyl isomerase domain and WD repeat-containing protein 1 (human)
Definition A peptidylprolyl isomerase domain and WD repeat-containing protein 1 that is encoded in the genome of human.
Short Label hPPWD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BP3 (PPWD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S5 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
Y274 Phosphorylation PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K394 Acetylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K422 Ubiquitination PhosphoSitePlus
K444 Acetylation PhosphoSitePlus
K444 Methylation PhosphoSitePlus
K445 Methylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T631 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K62 N62 Biomuta DOID:363 / uterine cancer [ tcga ]
K220 N220 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K258 R258 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K258 N258 Biomuta DOID:363 / uterine cancer [ tcga ]
S289 L289 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S289 * Biomuta DOID:3571 / liver cancer [ tcga ]