iPTMnet Report for Q96BI3 (APH1A)
Protein Information
| UniProt AC / UniProt ID | Q96BI3 / APH1A_HUMAN |
| Protein Name | Gamma-secretase subunit APH-1A |
| Gene Name | Name: APH1A Synonyms:PSF;ORFNames:CGI-78,UNQ579/PRO1141; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96BI3 |
| PRO Name | gamma-secretase subunit APH-1A (human) |
| Definition | A gamma-secretase subunit APH-1A that is encoded in the genome of human. |
| Short Label | hAPH1A |
| Category | organism-gene |
DAG ViewQ96BI3 (APH1A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C9 | Methylation | score1 | IEDB | 31844290 | ||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S242 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y256 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S257 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K246 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C9 | Y9 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S110 | L110 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] |
