iPTMnet Report for Q96BH1 (RNF25)
Protein Information
UniProt AC / UniProt ID | Q96BH1 / RNF25_HUMAN |
Protein Name | E3 ubiquitin-protein ligase RNF25 |
Gene Name | Name: RNF25 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96BH1 |
PRO Name | E3 ubiquitin-protein ligase RNF25 (human) |
Definition | An E3 ubiquitin-protein ligase RNF25 that is encoded in the genome of human. |
Short Label | hRNF25 |
Category | organism-gene |
Q96BH1 (RNF25) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K213 | Acetylation | score1 | PhosphoSitePlus | |||
S297 | Phosphorylation | score1 | PhosphoSitePlus | |||
K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
K334 | Ubiquitination | score1 | PhosphoSitePlus | |||
K341 | Ubiquitination | score1 | PhosphoSitePlus | |||
R348 | Methylation | score1 | PhosphoSitePlus | |||
K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
R422 | Methylation | score1 | PhosphoSitePlus | |||
Y432 | Phosphorylation | score1 | PhosphoSitePlus | |||
R434 | Methylation | score1 | PhosphoSitePlus | |||
R437 | Methylation | score1 | PhosphoSitePlus | |||
Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
R443 | Methylation | score1 | PhosphoSitePlus | |||
S450 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 18212344, 20068231, ... | ||
S455 | Phosphorylation | score1 | PhosphoSitePlus | |||
K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
S459 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S90 | T90 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S90 | L90 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
R348 | Q348 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
R348 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S391 | N391 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R422 | C422 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ] | |
R422 | S422 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
R434 | H434 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
R434 | C434 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
R437 | Q437 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R437 | W437 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
R443 | W443 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] |