iPTMnet Report for Q96BH1 (RNF25)
Protein Information
| UniProt AC / UniProt ID | Q96BH1 / RNF25_HUMAN |
| Protein Name | E3 ubiquitin-protein ligase RNF25 |
| Gene Name | Name: RNF25 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96BH1 |
| PRO Name | E3 ubiquitin-protein ligase RNF25 (human) |
| Definition | An E3 ubiquitin-protein ligase RNF25 that is encoded in the genome of human. |
| Short Label | hRNF25 |
| Category | organism-gene |
Q96BH1 (RNF25) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K213 | Acetylation | score1 | PhosphoSitePlus | |||
| S297 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K334 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K341 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R348 | Methylation | score1 | PhosphoSitePlus | |||
| K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S391 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R422 | Methylation | score1 | PhosphoSitePlus | |||
| Y432 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R434 | Methylation | score1 | PhosphoSitePlus | |||
| R437 | Methylation | score1 | PhosphoSitePlus | |||
| Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R443 | Methylation | score1 | PhosphoSitePlus | |||
| S450 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 18212344, 20068231, ... | ||
| S455 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K456 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S459 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S90 | T90 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S90 | L90 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| R348 | Q348 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| R348 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S391 | N391 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R422 | C422 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:10283 / prostate cancer [ cosmic ] | |
| R422 | S422 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| R434 | H434 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| R434 | C434 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
| R437 | Q437 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R437 | W437 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R443 | W443 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] |
DAG View