iPTMnet Report for Q96BD8 (SKA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BD8 / SKA1_HUMAN
Protein Name Spindle and kinetochore-associated protein 1
Gene Name Name: SKA1
Synonyms:C18orf24;
Organism Homo sapiens (Human)

PRO ID PR:Q96BD8
DAG View
PRO Name spindle and kinetochore-associated protein 1 (human)
Definition A spindle and kinetochore-associated protein 1 that is encoded in the genome of human.
Short Label hSKA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BD8 (SKA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S4 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
K117 Sumoylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
Y176 Phosphorylation PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
R245 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T157 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:0070003 / blastoma [ cosmic ]
Y158 C158 Biomuta DOID:9256 / colorectal cancer [ icgc ]
R245 Q245 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]