iPTMnet Report for Q96BD8 (SKA1)
Protein Information
| UniProt AC / UniProt ID | Q96BD8 / SKA1_HUMAN |
| Protein Name | Spindle and kinetochore-associated protein 1 |
| Gene Name | Name: SKA1 Synonyms:C18orf24; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96BD8 |
| PRO Name | spindle and kinetochore-associated protein 1 (human) |
| Definition | A spindle and kinetochore-associated protein 1 that is encoded in the genome of human. |
| Short Label | hSKA1 |
| Category | organism-gene |
Q96BD8 (SKA1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330 | ||
| S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K117 | Sumoylation | score1 | PhosphoSitePlus | |||
| K117 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C142 | Methylation | score1 | IEDB | 31844290 | ||
| K153 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K203 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R245 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | T2 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S11 | C11 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T157 | I157 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R245 | Q245 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
DAG View