Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96BD5 / PF21A_HUMAN
Protein Name PHD finger protein 21A
Gene Name Name: PHF21A
Synonyms:BHC80,KIAA1696;ORFNames:BM-006;
Organism Homo sapiens (Human)

PRO ID PR:Q96BD5
DAG View
PRO Name PHD finger protein 21A (human)
Definition A PHD finger protein 21A that is encoded in the genome of human.
Short Label hPHF21A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96BD5 (PHF21A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K25 Ubiquitination PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
K65 Sumoylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
T122 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 35254053, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T124 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35254053, 30379171, 32574038, 32938750, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T125 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35254053, 30379171, 32574038, 32938750, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
S127 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 35254053, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T130 O-Glycosylation GlyGen 22661428
T131 O-Glycosylation GlyGen 22661428
T142 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 35254053, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T176 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
T270 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35254053, 30379171, 32574038, 32938750, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T272 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 35254053, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T273 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 35254053, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T273 Phosphorylation PhosphoSitePlus
T276 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...30379171, 32574038, 35254053, 34019948, 30059200, 35289036, 35132862, 22661428, 31492838, 36240223, 29351928, 28657654, 29237092
T276 Phosphorylation PhosphoSitePlus
S277 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35254053, 22661428, 30379171, 32574038, 32938750, 34019948, 30059200, 35289036, 35132862, 30620550, 31492838, 36240223, 29351928, 28657654, 29237092
S277 Phosphorylation PhosphoSitePlus
S280 O-Glycosylation GlyGen 32574038
R314 Methylation PhosphoSitePlus
T320 Phosphorylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
T350 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
Y400 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
T444 Phosphorylation PhosphoSitePlus   UniProt 19690332
T446 Phosphorylation PhosphoSitePlus
S447 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 19690332
S450 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
S455 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S478 Phosphorylation PhosphoSitePlus
K571 Ubiquitination PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
K588 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T201 Phosphorylation HPRD 20068231
T209 Phosphorylation HPRD   PhosphoSitePlus 20068231
T305 Phosphorylation HPRD 20068231
T351 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T124 A124 Biomuta DOID:184 / bone cancer [ cosmic ]
S127 Y127 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T131 P131 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R314 K314 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K334 T334 Biomuta DOID:4159 / skin cancer [ cosmic ]
S412 R412 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S447 P447 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S450 F450 Biomuta DOID:4159 / skin cancer [ cosmic ]