Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96B26 / EXOS8_HUMAN
Protein Name Exosome complex component RRP43
Gene Name Name: EXOSC8
Synonyms:OIP2,RRP43;
Organism Homo sapiens (Human)

PRO ID PR:Q96B26
DAG View
PRO Name exosome complex component RRP43 (human)
Definition An exosome complex component RRP43 that is encoded in the genome of human.
Short Label hEXOSC8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96B26 (EXOSC8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K6 Ubiquitination PhosphoSitePlus
Y13 Phosphorylation PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K183 Ubiquitination PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K183 N183 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]