iPTMnet Report for Q96B23 (ARK2N)
Protein Information
| UniProt AC / UniProt ID | Q96B23 / ARK2N_HUMAN |
| Protein Name | Protein ARK2N |
| Gene Name | Name: ARK2N Synonyms:ARKL1,C18orf25; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96B23 |
| PRO Name | protein C18orf25 (human) |
| Definition | A protein C18orf25 that is encoded in the genome of human. |
| Short Label | hC18orf25 |
| Category | organism-gene |
Q96B23 (ARK2N) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K2 | Sumoylation | score1 | PhosphoSitePlus | |||
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K21 | Acetylation | score1 | PhosphoSitePlus | |||
| K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K29 | Sumoylation | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S39 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
| S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S66 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 18220336, ... | ||
| S67 | Phosphorylation | score4 | PhosphoSitePlus UniProt | 35882232, 23186163 | ||
| S69 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332, 18669648 | ||
| S73 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
| T74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S76 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
| S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S143 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| S145 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
| S147 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T149 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T151 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S327 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 17081983 | ||
| S328 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 17081983 | ||
| S330 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 21406692, 17081983 | ||
| R347 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
| S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S355 | O-Glycosylation | score1 | GlyGen | 23301498, 29485866, 31373491 | ||
| S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S356 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K358 | Sumoylation | score1 | PhosphoSitePlus | |||
| K358 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S361 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y365 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S367 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S39 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S66 | Phosphorylation | score0 | HPRD | 18691976, 17525332, 18767875, ... | ||
| S67 | Phosphorylation | score0 | HPRD | 18212344 | ||
| S69 | Phosphorylation | score0 | HPRD | 17525332, 18669648, 19415658 | ||
| S145 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S327 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983 | ||
| S328 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983 | ||
| S330 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983 | ||
| S355 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S356 | Phosphorylation | score0 | HPRD | 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S39 | Phosphorylation | score0 | HPRD | 17525332 | ||
| S66 | Phosphorylation | score0 | HPRD | 18691976, 17525332, 18767875, ... | ||
| S67 | Phosphorylation | score0 | HPRD | 18212344 | ||
| S69 | Phosphorylation | score0 | HPRD | 17525332, 18669648, 19415658 | ||
| S145 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S248 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S266 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983 | ||
| S267 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983 | ||
| S269 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 17081983 | ||
| S294 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S295 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S66 | P66 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T135 | I135 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S140 | A140 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S294 | Y294 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| S294 | P294 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S355 | P355 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| S355 | Y355 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S361 | L361 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] |
DAG View