iPTMnet Report for Q96B01 (RAD51AP1)
Protein Information
| UniProt AC / UniProt ID | Q96B01 / R51A1_HUMAN |
| Protein Name | RAD51-associated protein 1 |
| Gene Name | Name: RAD51AP1 Synonyms:PIR51; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96B01 |
| PRO Name | RAD51-associated protein 1 (human) |
| Definition | A RAD51-associated protein 1 that is encoded in the genome of human. |
| Short Label | hRAD51AP1 |
| Category | organism-gene |
Q96B01 (RAD51AP1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K8 | Sumoylation | score1 | PhosphoSitePlus | |||
| Y13 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S14 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S19 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
| S21 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
| T66 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S120 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 21406692, ... | ||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S124 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S241 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
| S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S318 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S327 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S331 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K343 | Acetylation | score1 | PhosphoSitePlus | |||
| S351 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| T352 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| Y13 | Phosphorylation | score0 | HPRD | 19651622, 18669648 | ||
| S14 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
| S19 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
| S21 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
| T29 | Phosphorylation | score0 | HPRD | 17081983 | ||
| T66 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S103 | Phosphorylation | score0 | HPRD | 19413330, 19651622, 17525332, ... | ||
| S122 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S224 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S263 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| S277 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S301 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S310 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
| T333 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S334 | Phosphorylation | score0 | HPRD | 18669648 | ||
| T335 | Phosphorylation | score0 | HPRD | 20068231 |
Proteoform PPIs
| Protein 1 | Relation | Protein 2 | Source | PMID | |
|---|---|---|---|---|---|
| PR:Q96B01-2 (hRAD51AP1/iso:2) | Interaction | PR:Q06609 (hRAD51) | PRO | 9396801 | |
| PR:Q96B01-3 (hRAD51AP1/iso:3) | Interaction | PR:Q06609 (hRAD51) | PRO | 9396801 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S124 | N124 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| K169 | E169 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S174 | C174 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S224 | F224 | Biomuta | [ cosmic ] | |
| S241 | F241 | Biomuta | [ cosmic ] | |
| S263 | Y263 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S263 | P263 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S280 | Y280 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S280 | P280 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S301 | I301 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S310 | F310 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S318 | I318 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S327 | F327 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
DAG View