iPTMnet Report for Q96AY4 (TTC28)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AY4 / TTC28_HUMAN
Protein Name Tetratricopeptide repeat protein 28
Gene Name Name: TTC28
Synonyms:KIAA1043,TPRBK;
Organism Homo sapiens (Human)

PRO ID PR:Q96AY4
DAG View
PRO Name tetratricopeptide repeat protein 28 (human)
Definition A tetratricopeptide repeat protein 28 that is encoded in the genome of human.
Short Label hTTC28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AY4 (TTC28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S4 Phosphorylation PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
T16 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
S28 Phosphorylation PhosphoSitePlus   UniProt 19369195, 18669648, 24275569
S32 Phosphorylation PhosphoSitePlus
T42 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
Y108 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
S318 Phosphorylation IEDB 32387766
Y364 Phosphorylation PhosphoSitePlus
Y397 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
Y530 Phosphorylation PhosphoSitePlus
Y536 Phosphorylation PhosphoSitePlus
Y564 Phosphorylation PhosphoSitePlus
Y610 Phosphorylation PhosphoSitePlus
Y617 Phosphorylation PhosphoSitePlus
Y620 Phosphorylation PhosphoSitePlus
K665 Ubiquitination PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
K826 Ubiquitination PhosphoSitePlus
Y1047 Phosphorylation PhosphoSitePlus
Y1059 Phosphorylation PhosphoSitePlus
T1288 Phosphorylation PhosphoSitePlus
S1298 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
S1387 Phosphorylation PhosphoSitePlus
S1442 Phosphorylation PhosphoSitePlus
Y1445 Phosphorylation PhosphoSitePlus
S1700 Phosphorylation PhosphoSitePlus
S1713 Phosphorylation PhosphoSitePlus
S1770 Phosphorylation PhosphoSitePlus
S1948 Phosphorylation PhosphoSitePlus
Y2056 Phosphorylation PhosphoSitePlus
S2079 Phosphorylation PhosphoSitePlus
T2089 Phosphorylation PhosphoSitePlus
S2096 Phosphorylation PhosphoSitePlus
S2104 Phosphorylation PhosphoSitePlus   UniProt 18669648
T2105 Phosphorylation PhosphoSitePlus
S2108 Phosphorylation PhosphoSitePlus
T2113 Phosphorylation PhosphoSitePlus
S2117 Phosphorylation PhosphoSitePlus
S2120 Phosphorylation PhosphoSitePlus
S2136 Phosphorylation PhosphoSitePlus
S2139 Phosphorylation PhosphoSitePlus
S2190 O-Glycosylation GlyGen 30379171, 30059200, 30620550, ...35132862, 31492838, 35254053, 29237092
S2202 O-Glycosylation GlyGen 30379171, 32938750, 30059200, ...30620550, 35132862, 31492838, 35254053, 29237092
S2224 Phosphorylation PhosphoSitePlus   UniProt 24275569
S2227 Phosphorylation PhosphoSitePlus
T2230 Phosphorylation PhosphoSitePlus
S2239 Phosphorylation PhosphoSitePlus
S2241 Phosphorylation PhosphoSitePlus
S2246 O-Glycosylation GlyGen 30379171, 30059200, 30620550, ...35132862, 31492838, 35254053, 29237092
S2251 Phosphorylation PhosphoSitePlus   UniProt 23186163
T2253 Phosphorylation PhosphoSitePlus
S2258 Phosphorylation PhosphoSitePlus
S2271 Phosphorylation PhosphoSitePlus
S2292 Phosphorylation PhosphoSitePlus
S2293 Phosphorylation PhosphoSitePlus
Y2295 Phosphorylation PhosphoSitePlus
S2296 Phosphorylation PhosphoSitePlus
S2300 Phosphorylation PhosphoSitePlus
S2302 Phosphorylation PhosphoSitePlus
R2304 Methylation PhosphoSitePlus
S2307 Phosphorylation PhosphoSitePlus
S2321 Phosphorylation PhosphoSitePlus
S2331 Phosphorylation PhosphoSitePlus
S2335 Phosphorylation PhosphoSitePlus
T2367 Phosphorylation PhosphoSitePlus
S2371 Phosphorylation PhosphoSitePlus
R2379 Methylation PhosphoSitePlus
S2393 Phosphorylation PhosphoSitePlus   UniProt 20068231
S2398 Phosphorylation PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
S2463 Phosphorylation PhosphoSitePlus
S2471 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 L32 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
S318 R318 Biomuta DOID:363 / uterine cancer [ icgc ]
K665 E665 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y1059 C1059 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1298 N1298 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1387 L1387 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1700 L1700 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1713 G1713 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2117 R2117 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2136 L2136 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S2258 P2258 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T2367 R2367 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R2379 L2379 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S2398 T2398 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S2463 F2463 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]