iPTMnet Report for Q96AP7 (ESAM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AP7 / ESAM_HUMAN
Protein Name Endothelial cell-selective adhesion molecule precursor
Gene Name Name: ESAM
ORFNames:UNQ220/PRO246;
Organism Homo sapiens (Human)

PRO ID PR:Q96AP7
DAG View
PRO Name endothelial cell-selective adhesion molecule (human)
Definition An endothelial cell-selective adhesion molecule that is encoded in the genome of human.
Short Label hESAM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AP7 (ESAM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N169 N-Glycosylation GlyGen   UniProt 23090970, 29391424, 19159218, ...24190977
N213 N-Glycosylation GlyGen 29391424
C224 Methylation IEDB 31844290
K286 Ubiquitination PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
N307 N-Glycosylation GlyGen 29391424
T314 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T334 M334 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S366 Y366 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S388 F388 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]