iPTMnet Report for Q96AP4 (ZUP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AP4 / ZUP1_HUMAN
Protein Name Zinc finger-containing ubiquitin peptidase 1
Gene Name Name: ZUP1
Synonyms:C6orf113,ZUFSP;
Organism Homo sapiens (Human)

PRO ID PR:Q96AP4
DAG View
PRO Name zinc finger-containing ubiquitin peptidase 1 (human)
Definition A zinc finger-containing ubiquitin peptidase 1 that is encoded in the genome of human.
Short Label hZUP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AP4 (ZUP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
C45 Methylation IEDB 31844290
K76 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K262 Acetylation PhosphoSitePlus   UniProt 19608861
K262 Ubiquitination PhosphoSitePlus
K276 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
K522 Ubiquitination PhosphoSitePlus
K525 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
Y548 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 F3 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y119 C119 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S307 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K402 N402 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S569 Y569 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]