iPTMnet Report for Q96AP0 (ACD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AP0 / ACD_HUMAN
Protein Name Adrenocortical dysplasia protein homolog
Gene Name Name: ACD
Synonyms:PIP1;
Organism Homo sapiens (Human)

PRO ID PR:Q96AP0
DAG View
PRO Name adrenocortical dysplasia protein homolog (human)
Definition An adrenocortical dysplasia protein that is encoded in the genome of human.
Short Label hACD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AP0 (ACD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
K84 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
C151 Methylation IEDB 31844290
S162 Phosphorylation PhosphoSitePlus
S169 Phosphorylation Q9HC98 (NEK6) PhosphoSitePlus   Signor 27396482
C187 Methylation IEDB 31844290
C199 Methylation IEDB 29437277
S311 Phosphorylation PhosphoSitePlus
S313 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
C320 Methylation IEDB 31844290
S321 Phosphorylation PhosphoSitePlus
T325 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S343 Phosphorylation PhosphoSitePlus
S347 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus   UniProt 23186163
R351 Methylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
R364 Methylation IEDB   PhosphoSitePlus 27503676
K367 Methylation PhosphoSitePlus
C380 Methylation IEDB 31844290
K381 Ubiquitination PhosphoSitePlus
R383 Methylation PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
Y418 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S421 Phosphorylation HPRD 19664995
Site PTM Type PTM Enzyme Score Source PMID
S424 Phosphorylation HPRD 19664995


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S311 N311 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
C320 Y320 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S330 F330 Biomuta DOID:4159 / skin cancer [ cosmic ]
R351 H351 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
R383 W383 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R383 Q383 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y418 C418 Biomuta DOID:1324 / lung cancer [ cosmic ]