iPTMnet Report for Q96AG4 (LRRC59)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AG4 / LRC59_HUMAN
Protein Name Leucine-rich repeat-containing protein 59
Gene Name Name: LRRC59
ORFNames:PRO1855;
Organism Homo sapiens (Human)

PRO ID PR:Q96AG4
DAG View
PRO Name leucine-rich repeat-containing protein 59 (human)
Definition A leucine-rich repeat-containing protein 59 that is encoded in the genome of human.
Short Label hLRRC59
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AG4 (LRRC59) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 25944712
T2 Acetylation UniProt 25489052
K3 Acetylation IEDB 34357683
K14 Ubiquitination PhosphoSitePlus
S23 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 24275569
S25 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
K33 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
C48 S-Nitrosylation dbSNO 19483679, 2212679, 22126794
K50 Ubiquitination PhosphoSitePlus
C59 S-Nitrosylation dbSNO 19483679
K66 Ubiquitination PhosphoSitePlus
K71 Acetylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
K73 Acetylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
K108 Acetylation PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
C131 S-Nitrosylation dbSNO 19483679
K135 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
K207 Methylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
S305 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K40 N40 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K71 M71 Biomuta DOID:3571 / liver cancer [ cosmic ]
K73 N73 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T99 A99 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K207 * Biomuta DOID:4159 / skin cancer [ cosmic ]