iPTMnet Report for Q96AE4 (FUBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AE4 / FUBP1_HUMAN
Protein Name Far upstream element-binding protein 1
Gene Name Name: FUBP1
Organism Homo sapiens (Human)

PRO ID PR:Q96AE4
DAG View
PRO Name far upstream element-binding protein 1 (human)
Definition A far upstream element-binding protein 1 that is encoded in the genome of human.
Short Label hFUBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AE4 (FUBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
Y4 Phosphorylation PhosphoSitePlus
S5 O-Glycosylation GlyGen 34846842, 33214551, 34725712, ...31492838, 35254053, 23576270, 34019948, 33465208, 20305658, 32119511, 34229054
S12 O-Glycosylation GlyGen 34846842
K32 Ubiquitination PhosphoSitePlus
K44 Acetylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
S52 Phosphorylation PhosphoSitePlus   UniProt 23186163
S55 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y58 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455, 18698806
Y58 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
Y60 Phosphorylation PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K76 Acetylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K77 Acetylation PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
R118 Methylation PhosphoSitePlus
C132 Methylation IEDB 31844290
K133 Ubiquitination PhosphoSitePlus
S140 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
S147 O-Glycosylation GlyGen 33214551, 34725712, 31492838, ...35254053, 23576270, 34019948, 33465208, 20305658, 32119511, 34229054
S147 Phosphorylation PhosphoSitePlus
C148 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
T151 O-Glycosylation GlyGen 33465208
T151 Phosphorylation PhosphoSitePlus
T153 O-Glycosylation GlyGen 33465208
T153 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 15302935, ...18669648, 20068231
S156 O-Glycosylation GlyGen 33465208
S156 Phosphorylation PhosphoSitePlus
S159 O-Glycosylation GlyGen 33465208
S159 Phosphorylation PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
S195 O-Glycosylation GlyGen 33214551, 34725712, 31492838, ...35254053, 23576270, 34019948, 33465208, 20305658, 32119511, 34229054
K203 Ubiquitination PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K218 Acetylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus
K243 Acetylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus 18698806
Y268 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
S270 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
R308 Methylation PhosphoSitePlus
K312 Acetylation PhosphoSitePlus
K312 Sumoylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
R321 Methylation PhosphoSitePlus
R331 Methylation PhosphoSitePlus
R359 Methylation PhosphoSitePlus   UniProt 24129315
R361 Methylation PhosphoSitePlus   UniProt 24129315
R363 Methylation PhosphoSitePlus   UniProt 24129315
K394 Ubiquitination PhosphoSitePlus
T398 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
R430 Methylation PhosphoSitePlus
T432 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y438 Phosphorylation PhosphoSitePlus
Y589 Phosphorylation PhosphoSitePlus
Y590 Phosphorylation PhosphoSitePlus
K591 Acetylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
T601 O-Glycosylation GlyGen 33214551, 34725712, 31492838, ...35254053, 23576270, 34019948, 33465208, 20305658, 32119511, 34229054
Y618 Phosphorylation PhosphoSitePlus
Y619 Phosphorylation PhosphoSitePlus
Y625 Phosphorylation PhosphoSitePlus 18698806
Y625 Phosphorylation P12931 (SRC) PhosphoSitePlus 18698806
Y626 Phosphorylation PhosphoSitePlus
T629 Phosphorylation PhosphoSitePlus
S630 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 15302935, 18669648, ...19690332, 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation HPRD 18491316
S52 Phosphorylation HPRD 19413330
S55 Phosphorylation HPRD 19413330
Y58 Phosphorylation HPRD 15592455
S84 Phosphorylation HPRD 20068231
S99 Phosphorylation HPRD 18452278
S140 Phosphorylation HPRD 18669648
T153 Phosphorylation HPRD 19413330, 16964243, 19664995, ...18669648, 19415658, 20068231
T207 Phosphorylation HPRD 20068230
T229 Phosphorylation HPRD 20068231
Y625 Phosphorylation HPRD 20068231
Y626 Phosphorylation HPRD 19664995
T629 Phosphorylation HPRD 17081983, 20068231
S630 Phosphorylation HPRD 19413330, 17081983, 19664995, ...19651622, 18669648, 19415658, 20068231
Site PTM Type PTM Enzyme Score Source PMID
K77 Ubiquitination PhosphoSitePlus
S84 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
A2 V2 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S5 L5 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S5 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K32 R32 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K44 R44 Biomuta [ cosmic ]
Y58 * Biomuta DOID:1319 / brain cancer [ cosmic ]
Y60 * Biomuta DOID:1319 / brain cancer [ cosmic ]
K64 R64 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K76 E76 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K77 N77 Biomuta DOID:1324 / lung cancer [ cosmic ]
S99 Y99 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K161 E161 Biomuta DOID:1324 / lung cancer [ cosmic ]
K209 * Biomuta DOID:1319 / brain cancer [ cosmic ]
S270 L270 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S270 * Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K312 E312 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
R331 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
R359 Q359 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R430 C430 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]
R430 H430 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y438 C438 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K592 E592 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T601 A601 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
Y619 * Biomuta DOID:1319 / brain cancer [ cosmic ]
Y625 C625 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
Y626 N626 Biomuta DOID:1324 / lung cancer [ cosmic ]
T629 A629 Biomuta DOID:1324 / lung cancer [ cosmic ]