iPTMnet Report for Q96AC1 (FERMT2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AC1 / FERM2_HUMAN
Protein Name Fermitin family homolog 2
Gene Name Name: FERMT2
Synonyms:KIND2,MIG2,PLEKHC1;
Organism Homo sapiens (Human)

PRO ID PR:Q96AC1
DAG View
PRO Name fermitin family homolog 2 (human)
Definition A fermitin family homolog 2 that is encoded in the genome of human.
Short Label hFERMT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AC1 (FERMT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T32 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K68 Acetylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
R118 Methylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
T148 Phosphorylation IEDB 35494241
K153 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S159 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 17081983, 25646088, ...32104508, 18669648, 24275569, 19690332, 20068231
T172 Phosphorylation PhosphoSitePlus
S175 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S177 Phosphorylation PhosphoSitePlus
Y179 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S180 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S181 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y185 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
T192 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 26037143
Y193 Phosphorylation P12931 (SRC) PhosphoSitePlus   Signor 26037143
S199 Phosphorylation PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
S339 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983, 20068231
S351 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231, 24275569
Y378 Phosphorylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
Y395 Phosphorylation PhosphoSitePlus
S403 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
T416 Phosphorylation PhosphoSitePlus
R424 Methylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S523 Phosphorylation PhosphoSitePlus
K528 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
T536 Phosphorylation PhosphoSitePlus
S550 Phosphorylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
Y590 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S666 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S159 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S175 Phosphorylation HPRD 18669648, 20068231
Y179 Phosphorylation HPRD 18669648, 20068231
S180 Phosphorylation HPRD 18669648
S181 Phosphorylation HPRD 18669648, 20068231
S202 Phosphorylation HPRD 20068231
S229 Phosphorylation HPRD 20068231
S328 Phosphorylation HPRD 17081983
S339 Phosphorylation HPRD 19651622, 17081983, 20068231
S351 Phosphorylation HPRD 19664994, 20068231, 18452278
Y590 Phosphorylation HPRD 20068231
S666 Phosphorylation HPRD 19413330, 18691976, 19664994, ...19651622, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S523 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T32 N32 Biomuta DOID:3571 / liver cancer [ cosmic ]
T36 A36 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K56 E56 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K56 I56 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K67 N67 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K81 E81 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K107 N107 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K128 M128 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K128 N128 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T129 I129 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K154 Q154 Biomuta DOID:3571 / liver cancer [ cosmic ]
S159 Y159 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T172 A172 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S199 R199 Biomuta DOID:3571 / liver cancer [ cosmic ]
T204 P204 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y395 F395 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K533 M533 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T536 I536 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S633 P633 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]