iPTMnet Report for Q96AB3 (ISOC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AB3 / ISOC2_HUMAN
Protein Name Isochorismatase domain-containing protein 2
Gene Name Name: ISOC2
Organism Homo sapiens (Human)

PRO ID PR:Q96AB3
DAG View
PRO Name isochorismatase domain-containing protein 2 (human)
Definition An isochorismatase domain-containing protein 2 that is encoded in the genome of human.
Short Label hISOC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AB3 (ISOC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus   UniProt 18691976
C21 S-Nitrosylation dbSNO 25040305
K26 Acetylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
C107 S-Nitrosylation dbSNO 25040305
C114 S-Nitrosylation dbSNO 25040305
R144 Methylation PhosphoSitePlus
K178 Acetylation PhosphoSitePlus
K182 Acetylation PhosphoSitePlus
K185 Acetylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus   UniProt 24275569
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 18691976, 20068231
S218 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C114 Y114 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]