iPTMnet Report for Q96AA8 (JAKMIP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96AA8 / JKIP2_HUMAN
Protein Name Janus kinase and microtubule-interacting protein 2
Gene Name Name: JAKMIP2
Synonyms:JAMIP2,KIAA0555,NECC1;
Organism Homo sapiens (Human)

PRO ID PR:Q96AA8
DAG View
PRO Name Janus kinase and microtubule-interacting protein 2 (human)
Definition A Janus kinase and microtubule-interacting protein 2 that is encoded in the genome of human.
Short Label hJAKMIP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96AA8 (JAKMIP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S116 Phosphorylation PhosphoSitePlus
R122 Methylation PhosphoSitePlus
R130 Methylation PhosphoSitePlus
R138 Methylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
K241 Acetylation PhosphoSitePlus
K252 Acetylation PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K356 Acetylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
Y522 Phosphorylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
K753 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S116 F116 Biomuta DOID:4159 / skin cancer [ cosmic ]
R122 C122 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
R138 W138 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S196 L196 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S202 L202 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K252 N252 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S376 Y376 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S376 F376 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y522 S522 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K753 T753 Biomuta DOID:2531 / hematologic cancer [ cosmic ]