Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96A47 / ISL2_HUMAN
Protein Name Insulin gene enhancer protein ISL-2
Gene Name Name: ISL2
Organism Homo sapiens (Human)

PRO ID PR:Q96A47
DAG View
PRO Name insulin gene enhancer protein ISL-2 (human)
Definition An insulin gene enhancer protein ISL-2 that is encoded in the genome of human.
Short Label hISL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96A47 (ISL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S43 Phosphorylation PhosphoSitePlus
S154 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S157 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 18669648, ...15302935
K201 Ubiquitination PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus   UniProt 19690332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S43 L43 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]